Symbol
Name
ID

Ltbp4
latent transforming growth factor beta binding protein 4
MGI:1321395

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Patent foramen ovale	Right ventricular hypertrophy	Peripheral pulmonary artery stenosis	Vascular dilatation	Hypoplasia of the thymus	Accessory spleen
Disease(s) Associated with LTBP4
autosomal recessive cutis laxa type IC

Mouse Phenotypes

abnormal aorta morphology

abnormal aorta elastic fiber morphology

increased aorta wall thickness

increased myocardial fiber size

heart right ventricle hypertrophy

abnormal interventricular septum morphology

increased heart weight

enlarged heart

abnormal heart left ventricle morphology

increased heart right ventricle wall thickness

dilated heart ventricle

abnormal cardiovascular system physiology

cardiomyopathy

ventricular cardiomyopathy

Availability

Mouse Genotype

Ltbp4^{Gt(E301B04)Wrst}/Ltbp4^{Gt(E301B04)Wrst}

Ltbp4^{Gt(U3Cre)1Vmel}/Ltbp4^{Gt(U3Cre)1Vmel}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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